Anti-Neutrophil defensin 4/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Neutrophil defensin 4/FITC Conjugated抗体

Anti-Neutrophil defensin 4/FITC Conjugated抗体

商家询价

产品名称: Anti-Neutrophil defensin 4/FITC Conjugated抗体

英文名称: Anti-Neutrophil defensin 4/FITC

产品编号: YB--2799R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Neutrophil defensin 4/FITC Conjugated抗体

产品编号 YB-2799R-FITC
英文名称 Anti-Neutrophil defensin 4/FITC
中文名称 FITC标记的防御素α4抗体
别    名 Neutrophil defensin 4; Corticostatin; Defensin alpha 4; Defensin, alpha 4; HNP-4; HP-4; HNP 4; defensin, alpha 4, corticostatin; neutrophil defensin 4 precursor; neutrophil defensin 4 preproprotein; DEF4; DEFA4; DEF4_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3.8kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Defensin alpha 4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq].

Function:
Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.

Subunit:
Homodimer.

Subcellular Location:
Secreted.

Similarity:
Belongs to the alpha-defensin family.

Database links:

Entrez Gene: 1669 Human

Omim: 601157 Human

SwissProt: P12838 Human

Unigene: 591391 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.