Anti-CCR6/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-CCR6/FITC Conjugated抗体

Anti-CCR6/FITC Conjugated抗体

商家询价

产品名称: Anti-CCR6/FITC Conjugated抗体

英文名称: Anti-CCR6/FITC

产品编号: YB--1542R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-CCR6/FITC Conjugated抗体

产品编号 YB-1542R-FITC
英文名称 Anti-CCR6/FITC
中文名称 FITC标记的细胞表面趋化因子受体6抗体
别    名 CKR6; C-C chemokine receptor type 6; BN 1; BN1; C C chemokine receptor type 6; C C CKR 6; CC chemokine receptor type 6; CC CKR 6; CC R6; CCCKR6; CCR 6; CD 196; CD196; CD196 antigen; Chemokine (C C motif) receptor 6; Chemokine (C C) receptor 6; Chemokine (CC motif) receptor 6; Chemokine (CC) receptor 6; Chemokine receptor 6; Chemokine receptor like 3; CKR 6; CKR L3; CKRL3; CMKBR 6; CMKBR6; DCR 2; DCR2; DRY 6; DRY6; G protein coupled receptor 29; GPR 29; GPR CY4; GPR29; GPRCY 4; GPRCY4; LARC receptor; Seven transmembrane receptor lymphocyte 22; STRL 22; STRL22; CCR6_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  转录调节因子  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 Flow-Cyt=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCR6 (151-241aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP 3 alpha). This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.

Function:
Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 1235 Human

Entrez Gene: 12458 Mouse

Entrez Gene: 308163 Rat

Omim: 601835 Human

SwissProt: P51684 Human

SwissProt: O54689 Mouse

Unigene: 46468 Human

Unigene: 8007 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

CCR6/CD196也是是属于G蛋白偶联受体一家族成员,参与调节白细胞的迁移和活性作用,是细胞膜蛋白