Anti-CX3CL1/FITC Conjugated抗体
产品名称: Anti-CX3CL1/FITC Conjugated抗体
英文名称: Anti-CX3CL1/FITC
产品编号: YB--0811R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-CX3CL1/FITC Conjugated抗体
产品编号 | YB-0811R-FITC |
英文名称 | Anti-CX3CL1/FITC |
中文名称 | FITC标记的CX3CL1抗体 |
别 名 | C3Xkine; Chemokine C X3 C motif ligand 1; Chemokine CX3C Motif Ligand 1; CX3C membrane anchored chemokine; CXC 3; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; NTN; NTT; SCYD 1; SCYD1; Small inducible cytokine D1; Small inducible cytokine subfamily D (Cys X3 Cys) member 1; Small inducible cytokine subfamily D member 1; X3CL1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 41kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CX3CL1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion. Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Subunit: Monomer. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted. Tissue Specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Post-translational modifications: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. O-glycosylated with core 1 or possibly core 8 glycans. Similarity: Belongs to the intercrine delta family. Database links: Entrez Gene: 6376 Human Entrez Gene: 20312 Mouse Entrez Gene: 89808 Rat Omim: 601880 Human SwissProt: P78423 Human SwissProt: O35188 Mouse SwissProt: O55145 Rat Unigene: 531668 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神经趋化蛋白cx3cl1免疫应答应答及细胞附着,参与细胞因子和趋化因子介导信号转导、免疫细胞趋化性、调控炎症应答反应、白细胞附着激活、正调控钙非依赖细胞附着 |