Anti-CX3CL1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-CX3CL1/FITC Conjugated抗体

Anti-CX3CL1/FITC Conjugated抗体

商家询价

产品名称: Anti-CX3CL1/FITC Conjugated抗体

英文名称: Anti-CX3CL1/FITC

产品编号: YB--0811R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
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  • 邮编 : 200612
  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-CX3CL1/FITC Conjugated抗体

产品编号 YB-0811R-FITC
英文名称 Anti-CX3CL1/FITC
中文名称 FITC标记的CX3CL1抗体
别    名 C3Xkine; Chemokine C X3 C motif ligand 1; Chemokine CX3C Motif Ligand 1; CX3C membrane anchored chemokine; CXC 3; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; NTN; NTT; SCYD 1; SCYD1; Small inducible cytokine D1; Small inducible cytokine subfamily D (Cys X3 Cys) member 1; Small inducible cytokine subfamily D member 1; X3CL1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CX3CL1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.

Function:
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

Subunit:
Monomer.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.

Tissue Specificity:
Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

Post-translational modifications:
A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. 
O-glycosylated with core 1 or possibly core 8 glycans.

Similarity:
Belongs to the intercrine delta family.

Database links:

Entrez Gene: 6376 Human

Entrez Gene: 20312 Mouse

Entrez Gene: 89808 Rat

Omim: 601880 Human

SwissProt: P78423 Human

SwissProt: O35188 Mouse

SwissProt: O55145 Rat

Unigene: 531668 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

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