Anti-SOD2/FITC Conjugated抗体上海钰博生物科技有限公司

金牌供应商

性能参数

产品名称: Anti-SOD2/FITC Conjugated抗体
英文名称: Anti-SOD2/FITC
抗体货号: YB--1080R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human SOD2
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/6/4 12:59:00
详细资料:  实验方法技术资料
浏览人数:9
诚信指数:2562点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是3002799160,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

上海钰博生物科技有限公司
地址:
上海市沪闵路6088号龙之梦大厦8楼806室
邮编:
200612
电话:
021-60514606
传真:
021-60514606
联系人:
顾磊
所在区域:
上海·上海
邮件:
公司展台:
在线QQ:
我是3002799160,请问我有什么可以帮到您呢?
扫一扫,关注我们

产品详细描述

 Anti-SOD2/FITC Conjugated抗体

产品编号 YB-1080R-FITC
英文名称 Anti-SOD2/FITC
中文名称 FITC标记的超氧化物歧化酶2抗体
别    名 IPO B; Manganese SOD; Superoxide Dismutase 2; Manganese superoxide dismutase; Mn SOD; MNSOD; SOD 2; SOD-2; SOD2; Superoxide dismutase [Mn] mitochondrial; Superoxide dismutase [Mn] mitochondrial precursor; Superoxide dismutase 2 mitochondrial; SODM_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 神经生物学  细胞凋亡  激酶和***酸酶  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOD2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Function:
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Subunit:
Homotetramer.

Subcellular Location:
Mitochondrion matrix.

Post-translational modifications:
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity. 
Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting.

DISEASE:
Microvascular complications of diabetes 6 (MVCD6) [MIM:612634]: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Similarity:
Belongs to the iron/manganese superoxide dismutase family.

Database links:

Entrez Gene: 374042 Chicken

Entrez Gene: 281496 Cow

Entrez Gene: 476258 Dog

Entrez Gene: 6648 Human

Entrez Gene: 20656 Mouse

Entrez Gene: 100154319 Pig

Entrez Gene: 24787 Rat

Omim: 147460 Human

SwissProt: P41976 Cow

SwissProt: P04179 Human

SwissProt: P09671 Mouse

SwissProt: P41982 Rabbit

SwissProt: P07895 Rat

Unigene: 487046 Human

Unigene: 290876 Mouse

Unigene: 10488 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

SOD2是清除线粒体氧自由基的最主要的酶类,SOD2参与促进细胞分化和肿瘤发生。SOD2的表达缺乏与血管病变、新生儿致死、神经退行性病变有关联。SOD2过度表达与抵御细胞氧化损伤有关。
超氧化物歧化酶又称(Superoxide dismutase,简称SOD)是参与机体抗氧化(ROS,反应性氧离子reactive oxygen species)防御机制和抵御细胞氧化损伤最重要的酶类之一, 广泛存在于需氧生物、耐氧生物及某些厌氧微生物中,目前已知的SOD 主要分为三类,即胞质中Cu/Zn-SOD(即SOD1)、线粒体中的Mn-SOD(即SOD2)和ec-SOD(即SOD3)

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Anti-SOD2/FITC Conjugated抗体产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要