Anti-Semaphorin 3F/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Semaphorin 3F/FITC Conjugated抗体

Anti-Semaphorin 3F/FITC Conjugated抗体

商家询价

产品名称: Anti-Semaphorin 3F/FITC Conjugated抗体

英文名称: Anti-Semaphorin 3F/FITC

产品编号: YB--1122R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Semaphorin 3F/FITC Conjugated抗体

产品编号 YB-1122R-FITC
英文名称 Anti-Semaphorin 3F/FITC
中文名称 FITC标记的臂板蛋白3F抗体
别    名 Semaphorin-3F; Semaphorin3F; Sema III/F; Sema IV; sema3F; SemaIII/F; SemaIV; Semaphorin IV; SemaphorinIV; SEM3F_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 发育生物学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 88kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Sema3F
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family. 

Function:
May play a role in cell motility and cell adhesion.

Subunit:
Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Sema domain.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed abundantly but differentially in a variety of neural and nonneural tissues. There is high expression in mammary gland, kidney, fetal brain, and lung and lower expression in heart and liver.

Database links:

Entrez Gene: 6405 Human

Entrez Gene: 20350 Mouse

Entrez Gene: 315996 Rat

Omim: 601124 Human

SwissProt: Q13275 Human

SwissProt: O88632 Mouse

Unigene: 32981 Human

Unigene: 12903 Mouse

Unigene: 205616 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications