Anti-PAX9/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-PAX9/FITC Conjugated抗体
英文名称: Anti-PAX9/FITC
抗体货号: YB--1102R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human PAX9
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/5/16 10:34:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-PAX9/FITC Conjugated抗体

产品编号 YB-1102R-FITC
英文名称 Anti-PAX9/FITC
中文名称 FITC标记的配对盒基因9抗体
别    名 Paired box 9; Paired box gene 9; Paired box homeotic gene 9; Paired box protein 9; Paired box protein Pax 9; Paired box protein Pax9; Paired domain gene 9; PAX 9; PAX9_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  细胞凋亡  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAX9
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PAX9 is a member of the paired box (PAX) family of transcription factors. Proteins in this family typically contain a paired box domain, a paired type homeodomain and an octapeptide sequence. They are important during fetal development and have also been implicated in cancer growth.
The exact role of PAX9 is unclear, but it is thought to be involved in development of various organs, skeletal tissue and stratified squamous epithelia. Mutations in PAX9 have also been implicated in oligodontia, a type of tooth agenesis which is a common developmental anomoly in humans. 

Function:
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs (By similarity).

Subunit:
Interacts with KDM5B.

Subcellular Location:
Nucleus.

DISEASE:
ooth agenesis selective 3 (STHAG3) [MIM:604625]: A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Contains 1 paired domain.

Database links:

Entrez Gene: 5083 Human

Entrez Gene: 18511 Mouse

Entrez Gene: 362741 Rat

Omim: 167416 Human

SwissProt: P55771 Human

SwissProt: P47242 Mouse

SwissProt: Q2L4T2 Rat

Unigene: 132576 Human

Unigene: 609574 Human

Unigene: 5035 Mouse

Unigene: 82416 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

同源结构域蛋白(Homeodomain Proteins)
PAX9属于转录抑制因子PAXs的一种。在胚胎发育和肿瘤生长中起关键作用。其突变和某些肿瘤的发病有关

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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