Anti-phospho-FSCN1(Ser39)/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-phospho-FSCN1(Ser39)/FITC Conjugated抗体

Anti-phospho-FSCN1(Ser39)/FITC Conjugated抗体

商家询价

产品名称: Anti-phospho-FSCN1(Ser39)/FITC Conjugated抗体

英文名称: Anti-phospho-FSCN1(Ser39)/FITC

产品编号: YB--0772R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-phospho-FSCN1(Ser39)/FITC Conjugated抗体

产品编号 YB-0772R-FITC
英文名称 Anti-phospho-FSCN1(Ser39)/FITC
中文名称 FITC标记的磷酸化纤维束蛋白同源物1抗体
别    名 Fascin (phospho S39); Fascin (phospho S39); 55 kDa actin bundling protein; Actin bundling protein; FAN 1; FAN1; Fascin 1; Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus); Fascin homolog 1; Fascin1; FLJ38511; FSCN 1; FSCN1; HSN; p55; Singed (Drosophila) like (sea urchin fascin homolog like); Singed drosophila homolog like; Singed like (fascin homolog sea urchin) (Drosophila); Singed like protein; SNL; Strongylocentrotus purpuratus.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 细胞生物  信号转导  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, 
产品应用 Flow-Cyt=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human FSCN1 around the phosphorylation site of Ser39
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Human fascin is a highly conserved actin-bundling protein. Fascin, encoded by the human homolog for sn (hsn) gene, has been localized to microspikes and stress fibers of cultured cells where it is thought to be involved in the formation of microfilament bundles. It is expressed predominantly in dendritic cells. Lymphoid cells, myeloid cells and plasma cells are negative. However, Reed Sternberg cells in Hodgkin’s lymphoma are positive for fascin staining. Epstein-Barr virus may induce expression of fascin in B cells. 

Function:
Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.

Subcellular Location:
Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.

Similarity:
Belongs to the fascin family.

Database links:

Entrez Gene: 6624 Human

Entrez Gene: 14086 Mouse

Entrez Gene: 683788 Rat

Omim: 602689 Human

SwissProt: Q16658 Human

SwissProt: Q61553 Mouse

SwissProt: P85845 Rat

Unigene: 118400 Human

Unigene: 289707 Mouse

Unigene: 199526 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

肌动蛋白集束蛋白/圆线虫紫癜抗体。
FSCN1为细胞骨架肌动蛋白的一种,该蛋白有蛋白结合,桥连、肌动蛋白丝结合的功能。 主要参与细胞增殖、肌动蛋白细胞骨架组织和生物发生、肌动蛋白丝束形成