Anti-Thrombin receptor/ PAR1/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-Thrombin receptor/ PAR1/FITC Conjugated抗体
英文名称: Anti-Thrombin receptor/ PAR1/FITC
抗体货号: YB--0828R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human PAR1
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/7 14:20:00
详细资料:  实验方法技术资料
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诚信指数:2562点
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-Thrombin receptor/ PAR1/FITC Conjugated抗体

产品编号 YB-0828R-FITC
英文名称 Anti-Thrombin receptor/ PAR1/FITC
中文名称 FITC标记的蛋白酶激活受体-1抗体
别    名 SAR; BXR; Proteinase-activated receptor 1 precursor; Thrombin receptor; Coagulation factor II receptor; D15S227E; Prader-Willi/Angelman region-1; PAR1; Coagulation factor II receptor; CF2R; Coagulation factor II (thrombin) receptor; F2R; HTR; PAR 1; PAR1; Protease activated receptor 1; Proteinase activated receptor 1; Thrombin receptor; TR; PAR-1; Coagulation factor II receptor; Coagulation factor II receptor; PAR-1; PAR1_HUMAN; Proteinase activated receptor 1; Proteinase-activated receptor 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  激酶和***酸酶  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAR1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]

Function:
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Platelets and vascular endothelial cells.

Post-translational modifications:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2149 Human

Omim: 187930 Human

SwissProt: P56488 Baboon

SwissProt: P25116 Human

Unigene: 482562 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

PAR蛋白全称为蛋白酶体活化受体(Protease-activated receptors),又称:凝血酶受体(Thrombin Receptor)是独立家族的G蛋白偶联受体, 研究认为与炎症,实体肿瘤等密切相关。
PAR1蛋白是乳腺癌细胞侵润和迁移的必需因子,它是作为基质金属蛋白酶体1(MMP-1)的受体关键性作用,这一研究结果为研制新的抗癌药物提供新的靶点

 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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