Anti-NEURL/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-NEURL/FITC Conjugated抗体

Anti-NEURL/FITC Conjugated抗体

商家询价

产品名称: Anti-NEURL/FITC Conjugated抗体

英文名称: Anti-NEURL/FITC

产品编号: YB--11897R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-NEURL/FITC Conjugated抗体

产品编号 YB-11897R-FITC
英文名称 Anti-NEURL/FITC
中文名称 FITC标记的环指蛋白67抗体
别    名 NEURL; h neu; h neuralized 1; Neuralized homolog; Neuralized like protein 1; NEURL1; RING finger protein 67; RNF67; NEU1A_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NEURL/RNF67
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.

Function:
May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway

Subcellular Location:
Cell membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. 

Tissue Specificity:
Expressed in brain, testis, pituitary gland, pancreas and bone marrow. Also poorly expressed in an malignant astrocytomas and several neuroectodermal tumor cell lines. 

Post-translational modifications:
Myristoylation is a determinant of membrane targeting

Similarity:
Contains 2 NHR (neuralized homology repeat) domains. 
Contains 1 RING-type zinc finger. 

Database links:

Entrez Gene: 9148 Human

Omim: 603804 Human

SwissProt: O76050 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications