Anti-NEURL/FITC Conjugated抗体
产品名称: Anti-NEURL/FITC Conjugated抗体
英文名称: Anti-NEURL/FITC
产品编号: YB--11897R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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- 邮编 : 200612
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Anti-NEURL/FITC Conjugated抗体
产品编号 | YB-11897R-FITC |
英文名称 | Anti-NEURL/FITC |
中文名称 | FITC标记的环指蛋白67抗体 |
别 名 | NEURL; h neu; h neuralized 1; Neuralized homolog; Neuralized like protein 1; NEURL1; RING finger protein 67; RNF67; NEU1A_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 62kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NEURL/RNF67 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors. Function: May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway Subcellular Location: Cell membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. Tissue Specificity: Expressed in brain, testis, pituitary gland, pancreas and bone marrow. Also poorly expressed in an malignant astrocytomas and several neuroectodermal tumor cell lines. Post-translational modifications: Myristoylation is a determinant of membrane targeting Similarity: Contains 2 NHR (neuralized homology repeat) domains. Contains 1 RING-type zinc finger. Database links: Entrez Gene: 9148 Human Omim: 603804 Human SwissProt: O76050 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |