Anti-MIR16/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-MIR16/FITC Conjugated抗体

Anti-MIR16/FITC Conjugated抗体

商家询价

产品名称: Anti-MIR16/FITC Conjugated抗体

英文名称: Anti-MIR16/FITC

产品编号: YB--12039R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-MIR16/FITC Conjugated抗体

产品编号 YB-12039R-FITC
英文名称 Anti-MIR16/FITC
中文名称 FITC标记的膜蛋白相互作用蛋白RGS16抗体
别    名 EC 3.1.4.44; GDE1; Glycerophosphodiester phosphodiesterase 1; Membrane interacting protein of RGS16; RGS16 interacting membrane protein; GDE1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞膜受体  G蛋白偶联受体  G蛋白信号  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MIR16/GDE1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Function:
MIR6 has glycerophosphoinositol phosphodiesterase activity.

Subunit:
Interacts with RGS16 (By similarity). Interacts with PRAF2.

Subcellular Location:
Cytoplasmic. Membrane; Multi-pass membrane protein (By similarity). 

Tissue Specificity:
Widely expressed.

Post-translational modifications:
N-glycosylated

Similarity:
Belongs to the glycerophosphoryl diester phosphodiesterase family. 
Contains 1 GDPD domain. 

Database links:

Entrez Gene: 51573 Human

Omim: 605943 Human

SwissProt: Q9NZC3 Human

Unigene: 512607 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications