Anti-CLPS/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-CLPS/FITC Conjugated抗体

Anti-CLPS/FITC Conjugated抗体

商家询价

产品名称: Anti-CLPS/FITC Conjugated抗体

英文名称: Anti-CLPS/FITC

产品编号: YB--10088R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-CLPS/FITC Conjugated抗体

产品编号 YB-10088R-FITC
英文名称 Anti-CLPS/FITC
中文名称 FITC标记的胰辅脂酶抗体
别    名 Colipase; Colipase pancreatic; Pancreatic colipase preproprotein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  内分泌病  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLPS
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Function:
Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
Enterostatin has a biological activity as a satiety signal.

Subunit:
Forms a 1:1 stoichiometric complex with pancreatic lipase.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the pancreas.

Similarity:
Belongs to the colipase family.

Database links:

Entrez Gene: 1208 Human

Omim: 120105 Human

SwissProt: P04118 Human

Unigene: 1340 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications