Anti-HERC3/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-HERC3/FITC Conjugated抗体

Anti-HERC3/FITC Conjugated抗体

商家询价

产品名称: Anti-HERC3/FITC Conjugated抗体

英文名称: Anti-HERC3/FITC

产品编号: YB--15461R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-HERC3/FITC Conjugated抗体

产品编号 YB-15461R-FITC
英文名称 Anti-HERC3/FITC
中文名称 FITC标记的HERC3 E3泛素蛋白连接酶抗体
别    名 HECT domain and RCC1 like domain containing protein 3; Hect domain and RLD 3; HERC 3; KIAA0032; Probable E3 ubiquitin protein ligase HERC3; HERC3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应  
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 117kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HERC3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
HERC3 is a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity).

Subcellular Location:
Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.

Post-translational modifications:
Ubiquitinated; which promotes degradation by the proteasome.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 7 RCC1 repeats.

Database links:
UniProtKB/Swiss-Prot: Q15034.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications