Anti-MGLAP/GIG36/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-MGLAP/GIG36/FITC Conjugated抗体
英文名称: Anti-MGLAP/GIG36/FITC
抗体货号: YB--4315R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human MGLAP/GIG36
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/6/12 10:56:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-MGLAP/GIG36/FITC Conjugated抗体

产品编号 YB-4315R-FITC
英文名称 Anti-MGLAP/GIG36/FITC
中文名称 FITC标记的细胞生长抑制基因36蛋白抗体
别    名 MGP; Cell growth inhibiting gene 36 protein; Cell growth-inhibiting gene 36 protein; GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX; GIG36; Matrix Gla protein; MGLAP; MGP; MGP_HUMAN; NTI.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MGLAP/GIG36
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Function:
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Subcellular Location:
Secreted.

Post-translational modifications:
Requires vitamin K-dependent gamma-carboxylation for its function.

DISEASE:
Defects in MGP are the cause of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.

Similarity:
Belongs to the osteocalcin/matrix Gla protein family.
Contains 1 Gla (gamma-carboxy-glutamate) domain.

Database links:

Entrez Gene: 4256 Human

Entrez Gene: 17313 Mouse

Entrez Gene: 25333 Rat

Omim: 154870 Human

SwissProt: P08493 Human

SwissProt: P19788 Mouse

SwissProt: P08494 Rat

Unigene: 365706 Human

Unigene: 243085 Mouse

Unigene: 2379 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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