Anti-LRP2BP/FITC Conjugated抗体
产品名称: Anti-LRP2BP/FITC Conjugated抗体
英文名称: Anti-LRP2BP/FITC
产品编号: YB--18363R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 183****2235
- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-LRP2BP/FITC Conjugated抗体
产品编号 | YB-18363R-FITC |
英文名称 | Anti-LRP2BP/FITC |
中文名称 | FITC标记的低密度脂蛋白相关蛋白2结合蛋白抗体 |
别 名 | DKFZp761O0113; FLJ44965; KIAA1325; LR2BP_HUMAN; LRP2 binding protein; LRP2-binding protein; Lrp2bp; Megalin binding protein; Megalin-binding protein; MegBP. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LRP2BP |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: LRP2BP is a 347 amino acid protein that contains one TPR repeat and six Sel1-like repeats. Localized to the plasma membrane and throughout the cytoplasm, LRP2BP interacts with megalin (also known as LRP2) and, via this interaction, is thought to regulate megalin function. Specifically, LRP2BP acts as a scaffold protein that, through its TPR motifs, assists in the sequestration and/or the release of transcription factors that influence megalin’s affects on endocytosis and hormone release. LRP2BP is expressed in colon, testis, small intestine and blood leukocytes, as well as in pancreatic adenocarcinoma cells, suggesting a possible role for LRP2BP in carcinogenesis. Two isoforms of LRP2BP exist due to alternative splicing events. Function: May act as an adapter that regulates LRP2 function. Subcellular Location: Cytoplasm. Detected in a vesicular staining pattern close to the plasma membrane and throughout the cytoplasm. Similarity: Contains 6 Sel1-like repeats. Contains 1 TPR repeat. Database links: Entrez Gene: 55805 Human Entrez Gene: 67620 Mouse Entrez Gene: 290753 Rat Entrez Gene: 100073340 Zebrafish SwissProt: Q9P2M1 Human SwissProt: Q9D4C6 Mouse SwissProt: Q569C2 Rat SwissProt: A5PLI4 Zebrafish Unigene: 558513 Human Unigene: 383914 Mouse Unigene: 108662 Rat Unigene: 94415 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |