Anti-MANEA/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-MANEA/FITC Conjugated抗体

Anti-MANEA/FITC Conjugated抗体

商家询价

产品名称: Anti-MANEA/FITC Conjugated抗体

英文名称: Anti-MANEA/FITC

产品编号: YB--18652R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-MANEA/FITC Conjugated抗体

产品编号 YB-18652R-FITC
英文名称 Anti-MANEA/FITC
中文名称 FITC标记的甘露糖苷酶2抗体
别    名 2-mannosidase; 4932703L02; Alpha 1,2 endomannosidase; DKFZp686D20120; Endo alpha D mannosidase; ENDO; Endo-alpha mannosidase; Endomannosidase; FLJ12838; Glycoprotein endo alpha 1,2 mannosidase; Glycoprotein endo-alpha-1; Glycoprotein endo-alpha-1,2-mannosidase; hEndo; Mandaselin; MANEA; MANEA_HUMAN; Mannosidase endo alpha; OTTMUSP0000000508; RP23-424K9.1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Cat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MANEA
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Highly expressed in the liver and kidney. Expressed at lower levels in muscle, pancreas, heart, placenta, lung and brain.

Post-translational modifications:
Undergoes proteolytic cleavage in the C-terminal region.

Similarity:
Belongs to the glycosyl hydrolase 99 family.

Database links:

Entrez Gene: 79694 Human

Entrez Gene: 242362 Mouse

Entrez Gene: 140808 Rat

Omim: 612327 Human

SwissProt: Q5SRI9 Human

SwissProt: Q6NXH2 Mouse

SwissProt: Q5GF25 Rat

Unigene: 533323 Human

Unigene: 245602 Mouse

Unigene: 10855 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.