Anti-METTL1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-METTL1/FITC Conjugated抗体

Anti-METTL1/FITC Conjugated抗体

商家询价

产品名称: Anti-METTL1/FITC Conjugated抗体

英文名称: Anti-METTL1/FITC

产品编号: YB--18814R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235
  • 传真 : 021-60514606
  • 邮箱 : shybio@126.com

 Anti-METTL1/FITC Conjugated抗体

产品编号 YB-18814R-FITC
英文名称 Anti-METTL1/FITC
中文名称 FITC标记的甲基化样蛋白1抗体
别    名 C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like 1; Methyltransferase like protein 1; Methyltransferase-like protein 1; Mettl1; TRM8; TRMB_HUMAN; TRMT8; tRNA (guanine N(7) ) methyltransferase; tRNA (guanine(46)-N(7))-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; tRNA(m7G46) methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human METTL1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4.

Similarity:
Belongs to the methyltransferase superfamily. TrmB family.

Database links:

Entrez Gene: 511197 Cow

Entrez Gene: 4234 Human

Entrez Gene: 17299 Mouse

GenBank: BC000550 Human

Omim: 604466 Human

SwissProt: Q2YDF1 Cow

SwissProt: Q9UBP6 Human

SwissProt: Q9Z120 Mouse

Unigene: 42957 Human

Unigene: 251593 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.