Anti-NIPAL4/FITC Conjugated抗体
产品名称: Anti-NIPAL4/FITC Conjugated抗体
英文名称: Anti-NIPAL4/FITC
产品编号: YB--19251R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
- 联系人 : 陈环环
- 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
- 邮编 : 200612
- 所在区域 : 上海
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- 传真 : 021-60514606
- 邮箱 : shybio@126.com
Anti-NIPAL4/FITC Conjugated抗体
产品编号 | YB-19251R-FITC |
英文名称 | Anti-NIPAL4/FITC |
中文名称 | FITC标记的镁转运蛋白NIPAL4抗体 |
别 名 | 9530066K23Rik; ICHN; Ichthyin; ICHYN; Magnesium transporter NIPA4; NIPA like 4; NIPA like domain containing 4; NIPA-like protein 4; NIPA4_HUMAN; NIPAL4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4; RGD1309452; RP23-29H5.5. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 50kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NIPAL4 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010] Function: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. Subcellular Location: Membrane. Tissue Specificity: Highly expressed in brain, lung, stomach, keratinocytes and leukocytes, and in all other tissues tested except liver, thyroid and fetal brain. DISEASE: Defects in NIPAL4 are the cause of ichthyosis congenital autosomal recessive ichthyin-related (ARCII) [MIM:612281]. ARCII is a disorder of keratinization with abnormal differentiation and desquamation of the epidermis. The phenotype usually presents as non-bullous congenital ichthyosiform erythroderma (NCIE) with fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs. Some of the families may show a more lamellar phenotype (lamellar ichthyosis). Similarity: Belongs to the NIPA family. Database links: Entrez Gene: 348938 Human Entrez Gene: 214112 Mouse Omim: 609383 Human SwissProt: Q0D2K0 Human SwissProt: Q8BZF2 Mouse Unigene: 4285 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |