Anti-NIPAL4/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-NIPAL4/FITC Conjugated抗体
英文名称: Anti-NIPAL4/FITC
抗体货号: YB--19251R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human NIPAL4
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/11 12:02:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-NIPAL4/FITC Conjugated抗体

产品编号 YB-19251R-FITC
英文名称 Anti-NIPAL4/FITC
中文名称 FITC标记的镁转运蛋白NIPAL4抗体
别    名 9530066K23Rik; ICHN; Ichthyin; ICHYN; Magnesium transporter NIPA4; NIPA like 4; NIPA like domain containing 4; NIPA-like protein 4; NIPA4_HUMAN; NIPAL4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4; RGD1309452; RP23-29H5.5.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NIPAL4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010]

Function:
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway.

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in brain, lung, stomach, keratinocytes and leukocytes, and in all other tissues tested except liver, thyroid and fetal brain.

DISEASE:
Defects in NIPAL4 are the cause of ichthyosis congenital autosomal recessive ichthyin-related (ARCII) [MIM:612281]. ARCII is a disorder of keratinization with abnormal differentiation and desquamation of the epidermis. The phenotype usually presents as non-bullous congenital ichthyosiform erythroderma (NCIE) with fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs. Some of the families may show a more lamellar phenotype (lamellar ichthyosis).

Similarity:
Belongs to the NIPA family.

Database links:

Entrez Gene: 348938 Human

Entrez Gene: 214112 Mouse

Omim: 609383 Human

SwissProt: Q0D2K0 Human

SwissProt: Q8BZF2 Mouse

Unigene: 4285 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

 

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