Anti-MYO1A/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-MYO1A/FITC Conjugated抗体

Anti-MYO1A/FITC Conjugated抗体

商家询价

产品名称: Anti-MYO1A/FITC Conjugated抗体

英文名称: Anti-MYO1A/FITC

产品编号: YB--19166R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-MYO1A/FITC Conjugated抗体

产品编号 YB-19166R-FITC
英文名称 Anti-MYO1A/FITC
中文名称 FITC标记的肌球蛋白重链1抗体
别    名 BBM I; BBM-I; BBMI; Brush border myosin I; DFNA48; MIHC; MYHL; Myo1a; MYO1A_HUMAN; Myosin I heavy chain; Myosin, heavy polypeptide like (100kD); Myosin-IA.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 118kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MYO1A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]

Function:
Involved in directing the movement of organelles along actin filaments.

DISEASE:
Defects in MYO1A are the cause of deafness autosomal dominant type 48 (DFNA48) [MIM:607841]. DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Similarity:
Contains 3 IQ domains.
Contains 1 myosin head-like domain.

Database links:

Entrez Gene: 4640 Human

Entrez Gene: 432516 Mouse

Omim: 601478 Human

SwissProt: Q9UBC5 Human

SwissProt: O88329 Mouse

Unigene: 5394 Human

Unigene: 90450 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.