Anti-NNT1/BSF3/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-NNT1/BSF3/FITC Conjugated抗体
英文名称: Anti-NNT1/BSF3/FITC
抗体货号: YB--19304R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human NNT1/BSF3
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/12 9:20:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-NNT1/BSF3/FITC Conjugated抗体

产品编号 YB-19304R-FITC
英文名称 Anti-NNT1/BSF3/FITC
中文名称 FITC标记的神经营养因子1/B淋巴细胞刺激因子3抗体
别    名 B cell stimulating factor 3; B-cell-stimulating factor 3; BSF 3; BSF-3; BSF3; Cardiotrophin like cytokine; Cardiotrophin like cytokine factor 1; Cardiotrophin-like cytokine factor 1; CISS 2; CISS2; CLC; CLCF 1; Clcf1; CLCF1_HUMAN; Cold induced sweating syndrome 2; CRLF 1 associated cytokine like factor 1; CRLF1 associated cytokine like factor 1; Neurotrophin 1; Neurotrophin 1/B cell stimulating factor 3; Neurotrophin1; NNT 1; NNT-1; Novel neurotrophin 1; Novel neurotrophin-1; NR 6; NR6.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  生长因子和***  糖蛋白  淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NNT1/BSF3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor, B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

Function:
Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver.

DISEASE:
Defects in CLCF1 are the cause of cold-induced sweating syndrome type 2 (CISS2) [MIM:610313]. Cold-induced sweating syndrome (CISS) is an autosomal recessive disorder characterized by profuse sweating induced by cool surroundings (temperatures of 7 to 18 degrees Celsius). Additional abnormalities include a high-arched palate, nasal voice, depressed nasal bridge, inability to fully extend the elbows and kyphoscoliosis.

Similarity:
Belongs to the IL-6 superfamily.

Database links:

Entrez Gene: 23529 Human

Entrez Gene: 56708 Mouse

Entrez Gene: 365395 Rat

Omim: 607672 Human

SwissProt: Q9UBD9 Human

SwissProt: Q9QZM3 Mouse

Unigene: 502977 Human

Unigene: 347919 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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