Anti-SAE1/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-SAE1/FITC Conjugated抗体
英文名称: Anti-SAE1/FITC
抗体货号: YB--19364R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human SAE1,Isoform 2
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Human, Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/12 10:24:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-SAE1/FITC Conjugated抗体

品编号 YB-19364R-FITC
英文名称 Anti-SAE1/FITC
中文名称 FITC标记的泛素样蛋白SUMO1激活酶抗体
别    名 Activator of SUMO1; AOS 1; AOS1; FLJ3091; HSPC 140; HSPC140; SAE 1; Sae1; SAE1_HUMAN; Sentrin/SUMO activating protein AOS 1; Sentrin/SUMO activating protein AOS1; SUA 1; SUA1; SUMO 1 activating enzyme E1 N subunit; SUMO 1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; SUMO1 activating enzyme E1 N subunit; SUMO1 activating enzyme subunit 1; Ubiquitin like 1 activating enzyme E1A; Ubiquitin like protein SUMO 1 activating enzyme; Ubiquitin like protein SUMO1 activating enzyme; Ubiquitin-like 1-activating enzyme E1A; UBL E1A; UBLE 1A; UBLE1A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAE1,Isoform 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

Subunit:
Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expression level increases during S phase and drops in G2 phase (at protein level).

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the ubiquitin-activating E1 family.

Database links:

Entrez Gene: 10055 Human

Entrez Gene: 56459 Mouse

Entrez Gene: 308384 Rat

Omim: 613294 Human

SwissProt: Q9UBE0 Human

SwissProt: Q9R1T2 Mouse

SwissProt: Q6AXQ0 Rat

Unigene: 515500 Human

Unigene: 258530 Mouse

Unigene: 9014 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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