Anti-HRH4/FITC Conjugated抗体上海钰博生物科技有限公司

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产品名称: Anti-HRH4/FITC Conjugated抗体
英文名称: Anti-HRH4/FITC
抗体货号: YB--10993R-FITC
产品规格: 20ul/50ul/100ul/200ul
级    别: , 分析纯, 见说明书
产品产地: 中国/美国
品牌商标: Ybscience
价    格: 2980元
抗原: KLH conjugated synthetic peptide derived from mouse HRH4
抗原来源: Rabbit
抗体来源: Rabbit
适用物种: Mouse, Rat,
见说明书conjugate:见说明书
Isotype:见说明书
应用范围: 科研使用
更新时间: 2019/7/12 10:59:00
详细资料:  实验方法技术资料
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使用范围:仅限科研使用,不能应用于临床
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产品详细描述

 Anti-HRH4/FITC Conjugated抗体

产品编号 YB-10993R-FITC
英文名称 Anti-HRH4/FITC
中文名称 FITC标记的组织胺H4受体抗体
别    名 GPCR105; GPRv53; H4 antibody H4R; HH4R; Histamine H4 receptor; AXOR35; BG26; G protein coupled receptor 105; HRH4_HUMAN; SP9144.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  免疫学  信号转导  细胞凋亡  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse HRH4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Function:
The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist)

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 59340 Human

Entrez Gene: 225192 Mouse

Entrez Gene: 170704 Rat

Omim: 606792 Human

SwissProt: Q9H3N8 Human

SwissProt: Q91ZY2 Mouse

SwissProt: Q91ZY1 Rat

Unigene: 287388 Human

Unigene: 207073 Mouse

Unigene: 162272 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

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