Anti-NSUN5/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-NSUN5/FITC Conjugated抗体

Anti-NSUN5/FITC Conjugated抗体

商家询价

产品名称: Anti-NSUN5/FITC Conjugated抗体

英文名称: Anti-NSUN5/FITC

产品编号: YB--19480R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-NSUN5/FITC Conjugated抗体

产品编号 YB-19480R-FITC
英文名称 Anti-NSUN5/FITC
中文名称 FITC标记的甲基转移酶NSUN5抗体
别    名 FLJ10267; MGC986; NOL1; NOL1-related protein; NOL1/NOP2/Sun domain family member 5; NOL1R; NOP2/Sun domain family, member 5; NOP2/Sun domain family, member 5A; NSUN5; NSUN5_HUMAN; p120; Putative methyltransferase NSUN5; WBSCR20; WBSCR20A; Williams Beuren syndrome chromosome region 20A; Williams-Beuren syndrome chromosomal region 20A protein; Williams-Beuren syndrome critical region protein 20 copy A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 信号转导  干细胞  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NSUN5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Function:
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.

Tissue Specificity:
Ubiquitous. Detected in placenta, heart and skeletal muscle.

Post-translational modifications:
Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Note=NSUN5 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.

Similarity:
Belongs to the methyltransferase superfamily. RsmB/NOP family.

Database links:

Entrez Gene: 55695 Human

SwissProt: Q96P11 Human

Unigene: 647060 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications