Anti-RBM35A/ESRP1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-RBM35A/ESRP1/FITC Conjugated抗体

Anti-RBM35A/ESRP1/FITC Conjugated抗体

商家询价

产品名称: Anti-RBM35A/ESRP1/FITC Conjugated抗体

英文名称: Anti-RBM35A/ESRP1/FITC

产品编号: YB--19771R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-RBM35A/ESRP1/FITC Conjugated抗体

产品编号 YB-19771R-FITC
英文名称 Anti-RBM35A/ESRP1/FITC
中文名称 FITC标记的RNA结合蛋白35A抗体
别    名 Epithelial splicing regulatory protein 1; Esrp1; ESRP1_HUMAN; FLJ20171; RBM35A; RMB35A; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM35A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]

Function:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Epithelial cell-specific.

Similarity:
Belongs to the ESRP family.
Contains 3 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 538640 Cow

Entrez Gene: 487054 Dog

Entrez Gene: 100055214 Horse

Entrez Gene: 54845 Human

Entrez Gene: 207920 Mouse

Entrez Gene: 100156237 Pig

Entrez Gene: 500409 Rat

Omim: 612959 Human

SwissProt: Q6NXG1 Human

SwissProt: Q3US41 Mouse

SwissProt: B2RYD2 Rat

Unigene: 487471 Human

Unigene: 387719 Mouse

Unigene: 161971 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications