Anti-TIP120A/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-TIP120A/FITC Conjugated抗体

Anti-TIP120A/FITC Conjugated抗体

商家询价

产品名称: Anti-TIP120A/FITC Conjugated抗体

英文名称: Anti-TIP120A/FITC

产品编号: YB--19935R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 所在区域 : 上海
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  • 邮箱 : shybio@126.com

 Anti-TIP120A/FITC Conjugated抗体

产品编号 YB-19935R-FITC
英文名称 Anti-TIP120A/FITC
中文名称 FITC标记的TBP相互作用蛋白TIP120A抗体
别    名 CAND 1; Cand1; CAND1_HUMAN; Cullin associated and neddylation dissociated 1; Cullin associated and neddylation dissociated protein 1; Cullin associated NEDD8 dissociated protein 1; Cullin-associated and neddylation-dissociated protein 1; Cullin-associated NEDD8-dissociated protein 1; DKFZP434M1414; FLJ10114; FLJ10929; FLJ38691; FLJ90441; KIAA0829; p120 CAND1; TATA binding protein interacting protein 120A; TBP interacting protein; TBP interacting protein of 120 kDa A; TBP Interacting Protein TIP120A; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TIP120; TIP120 protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  表观遗传学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIP120A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Enhances transcription from various types of promoters (By similarity). Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins.

Subunit:
Interacts with TBP (By similarity). Part of a complex that contains CUL1 and RBX1. Interacts with unneddylated cullins: interacts with CUL1, CUL2, CUL3, CUL4A, CUL4B and CUL5. Does not bind neddylated CUL1. Interaction with cullins is abolished in presence of COMMD1, which antagonizes with CAND1 for interacting with cullins.

Subcellular Location:
Cytoplasm Nucleus.

Similarity:
Belongs to the CAND family.
Contains 27 HEAT repeats.

Database links:

Entrez Gene: 452060 Chimpanzee

Entrez Gene: 538086 Cow

Entrez Gene: 55832 Human

Entrez Gene: 71902 Mouse

Entrez Gene: 100173509 Orangutan

Entrez Gene: 117152 Rat

Omim: 607727 Human

SwissProt: A7MBJ5 Cow

SwissProt: Q86VP6 Human

SwissProt: Q6ZQ38 Mouse

SwissProt: Q5R6L5 Orangutan

SwissProt: P97536 Rat

Unigene: 546407 Human

Unigene: 203965 Mouse

Unigene: 32934 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications