Anti-Plakophilin 3/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-Plakophilin 3/FITC Conjugated抗体

Anti-Plakophilin 3/FITC Conjugated抗体

商家询价

产品名称: Anti-Plakophilin 3/FITC Conjugated抗体

英文名称: Anti-Plakophilin 3/FITC

产品编号: YB--12703R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-Plakophilin 3/FITC Conjugated抗体

产品编号 YB-12703R-FITC
英文名称 Anti-Plakophilin 3/FITC
中文名称 FITC标记的桥粒斑菲素蛋白3抗体
别    名 PKP 3 ; PKP3 ; PKP3_HUMAN ; Plakophilin 3b ; Plakophilin-3 ; Plakophilin3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plakophilin 3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Function:
May play a role in junctional plaques.

Subcellular Location:
Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.

Tissue Specificity:
Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.

Similarity:
Belongs to the beta-catenin family.
Contains 8 ARM repeats.

Database links:

Entrez Gene: 11187 Human

Entrez Gene: 56460 Mouse

Entrez Gene: 293619 Rat

Omim: 605561 Human

SwissProt: Q9Y446 Human

SwissProt: Q9QY23 Mouse

Unigene: 534395 Human

Unigene: 350037 Mouse

Unigene: 144803 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications