Anti-TCF7L1/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-TCF7L1/FITC Conjugated抗体

Anti-TCF7L1/FITC Conjugated抗体

商家询价

产品名称: Anti-TCF7L1/FITC Conjugated抗体

英文名称: Anti-TCF7L1/FITC

产品编号: YB--12891R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 邮箱 : shybio@126.com

 Anti-TCF7L1/FITC Conjugated抗体

产品编号 YB-12891R-FITC
英文名称 Anti-TCF7L1/FITC
中文名称 FITC标记的转录因子7样蛋白1抗体
别    名 bHLHb21; HMG box transcription factor 3; HMG box transcription factor; OTTMUSP00000023419; T cell factor 3; TCF 3; TCF-3; TCF3; Tcf7l1; TF7L1_HUMAN; Transcription factor 7 like 1 (T-cell specific, HMG-box); Transcription factor 7 like 1; Transcription factor 7-like 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 干细胞  转录调节因子  淋巴细胞  t-淋巴细胞  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TCF7L1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]

Function:
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Subcellular Location:
Nucleus.

Tissue Specificity:
Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium.

Similarity:
Belongs to the TCF/LEF family.
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 83439 Human

Entrez Gene: 21415 Mouse

Entrez Gene: 312451 Rat

Omim: 604652 Human

SwissProt: Q9HCS4 Human

SwissProt: Q9Z1J1 Mouse

Unigene: 516297 Human

Unigene: 440067 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications