Anti-PRMT2/FITC Conjugated抗体-抗体-抗体-生物在线
Anti-PRMT2/FITC Conjugated抗体

Anti-PRMT2/FITC Conjugated抗体

商家询价

产品名称: Anti-PRMT2/FITC Conjugated抗体

英文名称: Anti-PRMT2/FITC

产品编号: YB--8695R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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  • 邮箱 : shybio@126.com

 Anti-PRMT2/FITC Conjugated抗体

产品编号 YB-8695R-FITC
英文名称 Anti-PRMT2/FITC
中文名称 FITC标记的蛋白精氨酸甲基转移酶2抗体
别    名 ANM2_HUMAN; EC 2.1.1.; histone arginine N methyltransferase PRMT2; Histone-arginine N-methyltransferase PRMT2; HMT 1; HMT1 (hnRNP methyltransferase S. cerevisiae) like 1; HMT1; HMT1 hnRNP methyltransferase like 1; hnRNP methyltransferase (S. cerevisiae) like 1; hnRNP methyltransferase like 1; Hrmt1l1; MGC111373; PRMT 2; PRMT2 alpha; prmt2; PRMT2 beta; PRMT2 gamma; PRMT2 protein; PRMT2L2; Protein arginine methyltransferase 2; Protein arginine N methyltransferase 2; Protein arginine N-methyltransferase 2; Zf2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    状 Lyophilized or Liquid
浓    度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRMT2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

Subunit:
Self-associates. Interacts with RB1 and E2F1 (By similarity). Interacts with NCOA6 coactivator. Interacts (via SH3 domain) with PRMT8. Interacts with AR. Interacts with NFKBIA.Interacts with ESR1, ESR2, PGR, PPARG, RARA, RXRA and THRB.Interacts with HNRNPUL1. 

Subcellular Location:
Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure.

Tissue Specificity:
Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord.

Similarity:
Belongs to the protein arginine N-methyltransferase family. 
Contains 1 SH3 domain.

Database links:

Entrez Gene: 3275 Human

Entrez Gene: 15468 Mouse

Entrez Gene: 499420 Rat

Omim: 601961 Human

SwissProt: P55345 Human

SwissProt: Q9R144 Mouse

Unigene: 154163 Human

Unigene: 32020 Mouse

Unigene: 145566 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.