Anti-DDIT4 Polyclonal Antibody北京索莱宝科技有限公司

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性能参数

产品名称: Anti-DDIT4 Polyclonal Antibody
英文名称: Anti-DDIT4 Polyclonal Antibody
抗体货号: K107273P
产品规格: 50ul/100ul
级    别: ,
产品产地: 北京
品牌商标: Solarbio
价    格: 900/50ul;1600/100ul元
抗原: Recombinant protein of human DDIT4
抗原来源: 
抗体来源: Rabbit
适用物种: Human
应用范围: WB IHC
更新时间: 2019/9/5 11:49:00
详细资料:  实验方法技术资料
浏览人数:23
诚信指数:1311点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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供应商联系卡

北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
18435223305
传真:
010-56371281
联系人:
郭倩
所在区域:
北京·北京
邮件:
公司展台:
在线QQ:
我是3329726100,请问我有什么可以帮到您呢?
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产品详细描述

 

Anti-DDIT4 Polyclonal Antibody

品牌:Solarbio | 货号:K107273P

商品货号:商品品牌:规格基本售价:选择规格
K107273P-50ulSolarbio50ul960.00元
K107273P-100ulSolarbio100ul1600.00元
英文名称Anti-DDIT4 Polyclonal Antibody
宿主Rabbit
别名Dig2, FLJ20500, REDD-1, REDD1, RTP801
应用WB IHC
稀释比例WB 1:1000-3000. IHC 1:100-300.
交叉反应Human
蛋白分子量25kDa
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human DDIT4
Subcellular
Locations
Cytoplasm
Swiss ProtQ9NX09
克隆类型Polyclonal Antibody
背景资料Regulates cell growth, proliferation and survival via
inhibition of the activity of the mammalian target of
rapamycin complex 1 (mTORC1). Inhibition of mTORC1
is mediated by a pathway that involves DDIT4/REDD1, AKT1,
the TSC1-TSC2 complex and the GTPase RHEB. Plays an
important role in responses to cellular energy levels and
cellular stress, including responses to hypoxia and DNA
damage. Regulates p53/TP53-mediated apoptosis in
response to DNA damage via its effect on mTORC1 activity.
Its role in the response to hypoxia depends on the cell type;
it mediates mTORC1 inhibition in fibroblasts and
thymocytes, but not in hepatocytes (By similarity). Required
for mTORC1-mediated defense against viral protein
synthesis and virus replication (By similarity). Inhibits
neuronal differentiation and neurite outgrowth mediated by
NGF via its effect on mTORC1 activity. Required for normal
neuron migration during embryonic brain development.
Plays a role in neuronal cell death.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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