Anti-Securin Polyclonal Antibody北京索莱宝科技有限公司

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产品名称: Anti-Securin Polyclonal Antibody
英文名称: Anti-Securin Polyclonal Antibody
抗体货号: K107290P
产品规格: 50ul/100ul
级    别: ,
产品产地: 北京
品牌商标: Solarbio
价    格: 900/50ul;1600/100ul元
抗原: A synthetic peptide of human Securin
抗原来源: 
抗体来源: Rabbit
适用物种: Human
应用范围: WB IHC
更新时间: 2019/9/5 13:24:00
详细资料:  实验方法技术资料
浏览人数:5
诚信指数:1279点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
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北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
18435223305
传真:
010-56371281
联系人:
郭倩
所在区域:
北京·北京
邮件:
公司展台:
在线QQ:
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产品详细描述

 

Anti-Securin Polyclonal Antibody 

品牌:Solarbio | 货号:K107290P

商品货号:商品品牌:规格基本售价:选择规格
K107290P-50ulSolarbio50ul960.00元
K107290P-100ulSolarbio100ul1600.00元
英文名称Anti-Securin Polyclonal Antibody
宿主Rabbit
别名PTTG1;EAP1;HPTTG;PTTG;TUTR1
应用WB IHC
稀释比例WB 1:5000-8000. IHC 1:50-200.
交叉反应Human
蛋白分子量22kDa
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human Securin
Subcellular
Locations
Nucleus Cytoplasm
Swiss ProtO95997
克隆类型Polyclonal Antibody
背景资料The encoded protein is a homolog of yeast securin
proteins, which prevent separins from promoting sister
chromatid separation. It is an anaphase-promoting
complex (APC) substrate that associates with a separin until
activation of the APC. The gene product has transforming
activity in vitro and tumorigenic activity in vivo, and the
gene is highly expressed in various tumors. The gene
product contains 2 PXXP motifs, which are required for its
transforming and tumorigenic activities, as well as for its
stimulation of basic fibroblast growth factor expression.
It also contains a destruction box (D box) that is required for
its degradation by the APC. The acidic C-terminal region of
the encoded protein can act as a transactivation domain.
The gene product is mainly a cytosolic protein, although it
partially localizes in the nucleus. Three transcript variants
encoding the same protein have been found for this gene.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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