Anti-APP Polyclonal Antibody北京索莱宝科技有限公司

金牌供应商

性能参数

产品名称: Anti-APP Polyclonal Antibody
英文名称: Anti-APP Polyclonal Antibody
抗体货号: K107292P
产品规格: 50ul/100ul
级    别: ,
产品产地: 北京
品牌商标: Solarbio
价    格: 900/50ul;1600/100ul元
抗原: A synthetic peptide of human APP
抗原来源: 
抗体来源: Rabbit
适用物种: Human Mouse Rat
应用范围: IHC
更新时间: 2019/9/5 14:29:00
详细资料:  实验方法技术资料
浏览人数:7
诚信指数:1279点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是3329726100,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
18435223305
传真:
010-56371281
联系人:
郭倩
所在区域:
北京·北京
邮件:
公司展台:
在线QQ:
我是3329726100,请问我有什么可以帮到您呢?
扫一扫,关注我们

产品详细描述

 

Anti-APP Polyclonal Antibody  

品牌:Solarbio | 货号:K107292P

商品货号:商品品牌:规格基本售价:选择规格
K107301P-50ulSolarbio50ul960.00元
K107301P-100ulSolarbio100ul1600.00元
英文名称Anti-APP Polyclonal Antibody
宿主Rabbit
别名ABPP;APPI;CVAP;A4;AD1
应用IHC
稀释比例IHC 1:100-300.
交叉反应Human Mouse Rat
蛋白分子量87/80/85/77kDa
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human APP
Subcellular
Locations
Nucleus Cytoplasm Cell membrane
Swiss ProtP05067
克隆类型Polyclonal Antibody
背景资料Functions as a cell surface receptor and performs
physiological functions on the surface of neurons relevant
to neurite growth, neuronal adhesion and axonogenesis.
Interaction between APP molecules on neighboring cells
promotes synaptogenesis (PubMed:25122912). Involved in
cell mobility and transcription regulation through protein-
protein interactions. Can promote transcription activation
through binding to APBB1-KAT5 and inhibits Notch
signaling through interaction with Numb. Couples to
apoptosis-inducing pathways such as those mediated by
G(O) and JIP. Inhibits G(o) alpha ATPase activity (By
similarity). Acts as a kinesin I membrane receptor,
mediating the axonal transport of beta-secretase and
presenilin 1. Involved in copper homeostasis/oxidative
stress through copper ion reduction. In vitro, copper-
metallated APP induces neuronal death directly or is
potentiated through Cu2+-mediated low-density
lipoprotein oxidation. Can regulate neurite outgrowth
through binding to components of the extracellular
matrix such as heparin and collagen I and IV.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Anti-APP Polyclonal Antibody产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要