Anti-RFA2 Polyclonal Antibody北京索莱宝科技有限公司

金牌供应商

性能参数

产品名称: Anti-RFA2 Polyclonal Antibody
英文名称: Anti-RFA2 Polyclonal Antibody
抗体货号: K107500P
产品规格: 50ul/100ul
级    别: ,
产品产地: 北京
品牌商标: Solarbio
价    格: 900/50ul;1600/100ul元
抗原: A synthetic peptide of human RFA2
抗原来源: 
抗体来源: Rabbit
适用物种: Human Mouse
应用范围: WB IHC
更新时间: 2019/9/9 11:00:00
详细资料:  实验方法技术资料
浏览人数:9
诚信指数:1279点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是3329726100,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
18435223305
传真:
010-56371281
联系人:
郭倩
所在区域:
北京·北京
邮件:
公司展台:
在线QQ:
我是3329726100,请问我有什么可以帮到您呢?
扫一扫,关注我们

产品详细描述

 

Anti-RPA2 Polyclonal Antibody

品牌:Solarbio | 货号:K107500P
商品货号:商品品牌:规格基本售价:选择规格
K107500P-50ulSolarbio50ul960.00元
K107500P-100ulSolarbio100ul1600.00元
宿主Rabbit
英文名称Anti-RPA2 Polyclonal Antibody
别名REPA2;RP-A p32;RP-A p34;RPA32;RP-Ap32;
RP-Ap34;replication protein A2
应用WB IHC
稀释比例WB 1:5000-8000. IHC 1:50-200.
蛋白分子量29/38kDa
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human RFA2
Swiss ProtP15927
Subcellular
Locations
Nucleus Cytoplasm
克隆类型Polyclonal Antibody
背景资料As part of the heterotrimeric replication protein A complex
(RPA/RP-A), binds and stabilizes single-stranded DNA
intermediates, that form during DNA replication or upon
DNA stress. It prevents their reannealing and in parallel,
recruits and activates different proteins and complexes
involved in DNA metabolism. Thereby, it plays an essential
role both in DNA replication and the cellular response to
DNA damage. In the cellular response to DNA damage, the
RPA complex controls DNA repair and DNA damage
checkpoint activation. Through recruitment of ATRIP
activates the ATR kinase a master regulator of the DNA
damage response. It is required for the recruitment of the
DNA double-strand break repair factors RAD51 and RAD52
to chromatin in response to DNA damage. Also recruits to
sites of DNA damage proteins like XPA and XPG that are
involved in nucleotide excision repair and is required for
this mechanism of DNA repair. Plays also a role in base
excision repair (BER) probably through interaction with
UNG. Also recruits SMARCAL1/HARP, which is involved in
replication fork restart, to sites of DNA damage. May also
play a role in telomere maintenance.

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Anti-RFA2 Polyclonal Antibody产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要