Anti-ESR1 Monoclonal Antibody
产品名称: Anti-ESR1 Monoclonal Antibody
英文名称: Anti-ESR1 Monoclonal Antibody
产品编号: K000083M
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: solarbio
更新时间: 2023-08-11T10:26:26
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073
- 传真 :
- 邮箱 : 3193328036@qq.com
Anti-ESR1 Monoclonal Antibody
品牌:solarbio | 货号:K000083M
宿主 | Mouse |
---|---|
英文名称 | Anti-ESR1 Monoclonal Antibody |
别名 | ER;Era;ESR;ESRA;ESTRR;NR3A1 |
应用 | WB |
稀释比例 | WB 1:1000. |
蛋白分子量 | 66kDa |
Gene ID | 2099 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG2b |
免疫原 | Purified recombinant human ESR1 protein expressed in E.coli. |
性状 | 液体 |
Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic side Cytoplasmic side Golgi apparatus Nucleus Peripheral membrane protein Single-pass type I membrane protein |
Swiss Prot | P03372 |
克隆号 | 6F11-C3-G6 |
克隆类型 | Monoclonal Antibody |
背景资料 | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. |