Anti-PCNA Monoclonal Antibody

英文名称	Anti-PCNA Monoclonal Antibody
宿主	Mouse
别名	ATLD2;cb16;Cyclin;HGCN872;MGC8367
应用	WB IP ICC IHC
稀释比例	WB 1:1000. ICC 1:100.
蛋白分子量	29kDa
Gene ID	5111
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Fractional precipitation
亚型	IgG2b
免疫原	Purified recombinant human PCNA protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human PCNA protein fragments expressed in E.coli.
Subcellular Locations	Nucleus
Swiss Prot	P12004
克隆号	2E1-G10-H10
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage,this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.[provided by RefSeq,Jul 2008]