Anti-RUVBL1 Polyclonal Antibody北京索莱宝科技有限公司

金牌供应商

性能参数

产品名称: Anti-RUVBL1 Polyclonal Antibody
英文名称: Anti-RUVBL1 Polyclonal Antibody
抗体货号: K108739P
产品规格: 
产品产地: 北京
品牌商标: Solarbio
价    格: 询价
抗原来源: 
抗体来源: Rabbit
适用物种: Human Mouse Rat Monkey
应用范围: WB IHC
更新时间: 2021/1/15 15:13:00
详细资料:  实验方法技术资料
浏览人数:86
诚信指数:1451点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
点此求购
在线QQ: 我是405465416,请问我有什么可以帮到您呢?
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

供应商联系卡

北京索莱宝科技有限公司
地址:
北京市通州区马驹桥镇联东U谷景盛南四街15号85A三层
邮编:
101102
电话:
010-50973129
传真:
010-56371281
联系人:
张净花
所在区域:
北京·北京
邮件:
公司展台:
在线QQ:
我是405465416,请问我有什么可以帮到您呢?
扫一扫,关注我们

产品详细描述

Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. Proposed core component of the chromatin remodeling INO80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. Plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. Essential for cell proliferation. May be able to bind plasminogen at cell surface and enhance plasminogen activation. 

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

查看Anti-RUVBL1 Polyclonal Antibody产品的用户还对以下产品感兴趣

暂无

ADVERTISEMENT

找不到您所需的产品,发布求购试试?

标题:*
描述:
姓名:*
Email:*
单位:*
电话:*
地址:*
邮编:
资料: 需要 不需要
报价: 需要 不需要