FcRn-Specific抗体-抗体-抗体-生物在线
FcRn-Specific抗体

FcRn-Specific抗体

商家询价

产品名称： FcRn-Specific抗体

英文名称： FcRn-SpecificAntibody

产品编号： XY16190-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 FCRN-SPECIFIC抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Published applications IF, WB Publications 2 citations –view here
Species specificity Human; other species not tested.
Published Species Dog, guinea pig
Images
Prev1NextView more validation data
  • 16190-1-AP;human placenta tissuehuman placenta tissue were subjected to SDS PAGE followed by western blot with 16190-1-AP(FCGRT-Specific antibody) at dilution of 1:300
Positive WB detected in Human placenta tissue, human liver tissue
Recommended dilution WB : 1:200-1:1000
 FCRN-SPECIFIC抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name Fc fragment of IgG, receptor, transporter, alpha
Calculated molecular
weight		 40 kDa Observed molecular 
weight		 35 kDa
GenBank accession 
number		 NM_004107 Gene ID (NCBI) 2217
Gene symbol FCGRT Synonyms Alpha chain, FCGRT, FCRN, Neonatal Fc receptor
Background FCRN-SPECIFIC抗体

The neonatal Fc receptor for IgG (FcRn) is a membrane-associated receptor which acts as a key determinant of IgG homeostasis. FcRn is similar in structure to major histocompatibility class I molecules. It is a heterodimer composed of a alpha chain associated with β2-microglobulin. FcRn transfers IgG from the mother to the fetus across the placenta and the proximal small intestine. In addition, throughout life, FcRn protects IgG from degradation and thus regulates the serum half-life of IgG (PMID: 17703228). FCRN-SPECIFIC抗体

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