IA-2/PTPRN抗体-抗体-抗体-生物在线
IA-2/PTPRN抗体

IA-2/PTPRN抗体

商家询价

产品名称： IA-2/PTPRN抗体

英文名称： IA-2/PTPRNAntibody

产品编号： XY10584-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 IA-2/PTPRN抗体

Applications
In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse, Rat; other species not tested.
Images
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  • 10584-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 10584-1-AP(PTPRN antibody) at dilution of 1:300
  • 10584-1-AP;mouse brain tissueIP Result of anti-PTPRN (IP:10584-1-AP, 3ug; Detection:10584-1-AP 1:600) with mouse brain tissue lysate 7000ug.
  • 10584-1-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 10584-1-AP(PTPRN antibody) at dilution of 1:50 (under 10x lens)
Positive WB detected in Mouse brain tissue, HEK-293 cells, mouse kidney tissue, rat brain tissue
Positive IP detected in Mouse brain tissue
Positive IHC detected in Human pancreas cancer tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
IA-2/PTPRN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen InformationIA-2/PTPRN抗体
Immunogen IA-2/PTPRN fusion protein ag0923 Full name Protein tyrosine phosphatase, receptor type, N
Calculated molecular
weight		 105 kDa Observed molecular 
weight		 60-65kd,106-115kd
GenBank accession 
number		 BC007713 Gene ID (NCBI) 5798
Gene symbol PTPRN Synonyms FLJ16131, IA 2, IA 2/PTP, IA2, ICA 512, ICA3, ICA512, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA 2, PTPRN, R PTP N
Background

IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell).(PMID: 10027571). IA-2/PTPRN was found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.IA-2/PTPRN抗体

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