TRIM38抗体-抗体-抗体-生物在线
TRIM38抗体

TRIM38抗体

商家询价

产品名称： TRIM38抗体

英文名称： TRIM38Antibody

产品编号： XY13405-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 TRIM38抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 13405-1-AP;human liver tissuehuman liver tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP(TRIM38 antibody) at dilution of 1:800
Positive WB detected in Human liver tissue, HEK-293 cells, human colon tissue
Recommended dilution WB : 1:500-1:5000
 TRIM38抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen TRIM38 fusion protein ag3840 Full name Tripartite motif-containing 38
Calculated molecular
weight		 465aa,53 kDa Observed molecular 
weight		 53 kDa
GenBank accession 
number		 BC026930 Gene ID (NCBI) 10475
Gene symbol TRIM38 Synonyms RING finger protein 15, RNF15, RORET, TRIM38, tripartite motif containing 38, Zinc finger protein RoRet
Background TRIM38抗体

The proinflammatory cytokines TNFα and IL-1β play central roles in many diseases, including infectious diseases, autoimmunity, and cancers. TRIM38 belongs to the TRIM protein family that is involved in various biological processes, including cell proliferation and apoptosis, innate immunity, and inflammatory response. It has been shown that TRIM38 acts as a suppressor in TOLL-like receptor (TLR)-mediated IFN-β induction by promoting degradation of TRAF6 and NAP1 through the ubiquitinproteasome system. (PMID:24434549) TRIM38抗体

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