Zyxin抗体-抗体-抗体-生物在线
Zyxin抗体

Zyxin抗体

商家询价

产品名称： Zyxin抗体

英文名称： ZyxinAntibody

产品编号： XY10330-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802
  • 传真 : 021-37680378
  • 邮箱 : shxysw02@163.com
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 ZYXIN抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Published applications IF, WB Publications 3 citations –view here
Species specificity Human; other species not tested.
Published Species Mouse
Images
Prev1NextView more validation data
  • 10330-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10330-1-AP(ZYX antibody) at dilution of 1:1000
Positive WB detected in HeLa cells, MCF7 cells
Recommended dilution WB : 1:200-1:2000
 ZYXIN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information ZYXIN抗体
Immunogen Zyxin fusion protein ag0419 Full name Zyxin
Calculated molecular
weight		 80 kDa Observed molecular 
weight		 78kd
GenBank accession 
number		 BC008743 Gene ID (NCBI) 7791
Gene symbol ZYX Synonyms ESP 2, HED 2, ZYX, zyxin, Zyxin 2
Background

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. ZYXIN抗体

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