KIF15,驱动蛋白家族成员15抗体

产品编号HZ-7804R
英文名称KIF15
中文名称驱动蛋白家族成员15抗体
别 名Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Serologically defined breast cancer antigen NY BR 62; Serologically defined breast cancer antigen NYBR62; FLJ25667; KIF15_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞周期蛋白 细胞骨架 细胞外基质 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat,
KIF15,驱动蛋白家族成员15抗体产品应用IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量160kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human KIF15
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KIF15,驱动蛋白家族成员15抗体PubMedPubMed
产品介绍background:
KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.

Function:
Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly.

Subunit:
Interacts with MKI67 and TPX2.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules.

Tissue Specificity:
Expressed in testis, colon, thymus and inbreast cancer.

KIF15,驱动蛋白家族成员15抗体Similarity:
Belongs to the kinesin-like protein family. KLP2subfamily.
Contains 1 kinesin-motor domain.

Gene ID:
56992

Database links:
Entrez Gene: 56992 Human
Entrez Gene: 209737 Mouse
Entrez Gene: 353302 Rat
SwissProt: Q9NS87 Human
SwissProt: Q6P9L6 Mouse
SwissProt: Q7TSP2 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.