PI14,蛋白酶抑制剂14抗体

产品编号HZ-9514R
英文名称PI14
中文名称蛋白酶抑制剂14抗体
别 名MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specific protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine (or cysteine) proteinase inhibitor clade I (neuroserpin) member 2; Serine (or cysteine) proteinase inhibitor clade I (pancpin) member 2; Serpin I2; Serpin peptidase inhibitor clade I (pancpin) member 2; TSA2004; SPI2_HUMAN; SERPINI2.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse,
PI14,蛋白酶抑制剂14抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量44kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SERPINI2/PI14
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PI14,蛋白酶抑制剂14抗体PubMedPubMed
产品介绍background:
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed in pancreas and adipose tissues.

Similarity:
Belongs to the serpin family.

PI14,蛋白酶抑制剂14抗体Database links:
Entrez Gene: 5276 Human
Entrez Gene: 67931 Mouse
Entrez Gene: 171149 Rat
Omim: 605587 Human
SwissProt: O75830 Human
SwissProt: Q9JK88 Mouse
Unigene: 445555 Human
Unigene: 259446 Mouse
Unigene: 54500 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.