HGFA,肝细胞生长因子激活蛋白/HGF activator抗体

产品编号HZ-9913R
英文名称HGFA
中文名称肝细胞生长因子激活蛋白/HGF activator抗体
别 名Hepatocyte growth factor activator; HGF activator preproprotein; HGFA; HGFA_HUMAN; HGF activator.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 生长因子和激素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog,
HGFA,肝细胞生长因子激活蛋白/HGF activator抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human HGFA/HGF activator
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
HGFA,肝细胞生长因子激活蛋白/HGF activator抗体PubMedPubMed
产品介绍background:
HGF activator belongs to the peptidase family S1 and activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. HGF Activator is produced as a zymogen, and the form found in serum is largely the inactive single-chain form. It is activated to a heterodimeric form by endoproteolytic processing.

Function:
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

Subunit:
Heterodimer of a short chain and a long chain linked by a disulfide bond.

Subcellular Location:
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.

Tissue Specificity:
Liver.

Similarity:
Belongs to the peptidase S1 family.
Contains 2 EGF-like domains.
Contains 1 fibronectin type-I domain.
Contains 1 fibronectin type-II domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain.

HGFA,肝细胞生长因子激活蛋白/HGF activator抗体Database links:
Entrez Gene: 6692 Human
Omim: 605123 Human
SwissProt: O43278 Human
Unigene: 233950 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.