FITC标记的同源盒蛋白HOXC5抗体-抗体-抗体-生物在线
FITC标记的同源盒蛋白HOXC5抗体

FITC标记的同源盒蛋白HOXC5抗体

商家询价

产品名称: FITC标记的同源盒蛋白HOXC5抗体

英文名称: Anti-HOXC5/FITC

产品编号: HZ-11589R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
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  • 所在区域 : 上海
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 Rabbit Anti-HOXC5/FITC Conjugated antibody

FITC标记的同源盒蛋白HOXC5抗体

 

产品编号 bs-11589R-FITC
英文名称 Anti-HOXC5/FITC
中文名称 FITC标记的同源盒蛋白HOXC5抗体
别    名 CP11; homeo box C5; homeobox C5; Homeobox protein CP11; homeobox protein Hox C5; Homeobox protein Hox-3D; Homeobox protein Hox-C5; Hox 3D; HOX3; HOX3D; HOXC5; HXC5_HUMAN; OTTHUMP00000217386.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXC5 (151-222aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:
UniProtKB/Swiss-Prot: Q00444.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

Hox同源框基因编码的蛋白是转录调控因子,在胚胎发育中起着重要作用。HOXC5是一个222个氨基酸的蛋白质,定位于细胞核,并含有一个同源盒DNA结合结构域。HOXC5作为多个交替剪接的异构体存在,作为序列特异性DNA结合转录因子,其是在发育过程中提供具有位置身份的细胞的调节机制的一部分。编码HOXC5的基因编码到12号染色体上的Hox蛋白簇,这是形态发生所必需的。在1亿3200万个碱基中编码超过1100个基因,染色体12构成人类基因组的4.5%。许多骨骼畸形与12号染色体相连,包括软骨发育不良、软骨发育不全和最不典型增生。