FITC标记的锌指蛋白Zdhhc18抗体
产品名称: FITC标记的锌指蛋白Zdhhc18抗体
英文名称: Anti-ZDHHC-18/FITC
产品编号: HZ-8641R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-ZDHHC-18/FITC Conjugated antibody
FITC标记的锌指蛋白Zdhhc18抗体
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZDHHC-18 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins. Function: Has palmitoyltransferase activity towards HRAS and LCK. Subcellular Location: Membrane; Multi-pass membrane protein Similarity: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. Contains 1 DHHC-type zinc finger. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
锌指蛋白含有DNA结合结构域,具有广泛的功能,其中大部分包含某种形式的转录激活或抑制。ZDHHC1(锌指,含1的DHHC型),也称为ZNF37 7(锌指蛋白377)或C16ORF1,是含有一个DHHC型锌指的485氨基酸多程膜蛋白。在胎儿心脏、肺和肾脏中表达,并且在成人肺和胰腺中也存在,ZDHHC1起棕榈酰基转移酶的作用,它催化棕榈酰辅酶A和蛋白半胱氨酸转化为S-棕榈酰蛋白和辅酶A。如ZDHHC1、ZDHHC5、ZDHHC6、ZDHHC7和ZDHHC18各自含有一种DHHC型锌指,通过它们向广泛范围的底物(包括H-ras、SNAP 25和GABAA R蛋白)传递棕榈酰转移酶活性。