FITC标记的锌指蛋白Zdhhc18抗体-抗体-抗体-生物在线
FITC标记的锌指蛋白Zdhhc18抗体

FITC标记的锌指蛋白Zdhhc18抗体

商家询价

产品名称: FITC标记的锌指蛋白Zdhhc18抗体

英文名称: Anti-ZDHHC-18/FITC

产品编号: HZ-8641R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-ZDHHC-18/FITC Conjugated antibody

FITC标记的锌指蛋白Zdhhc18抗体

 

产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZDHHC-18
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

Function:
Has palmitoyltransferase activity towards HRAS and LCK.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Contains 1 DHHC-type zinc finger.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
   
   
   
   
   
   
   
   
   
   

锌指蛋白含有DNA结合结构域,具有广泛的功能,其中大部分包含某种形式的转录激活或抑制。ZDHHC1(锌指,含1的DHHC型),也称为ZNF37 7(锌指蛋白377)或C16ORF1,是含有一个DHHC型锌指的485氨基酸多程膜蛋白。在胎儿心脏、肺和肾脏中表达,并且在成人肺和胰腺中也存在,ZDHHC1起棕榈酰基转移酶的作用,它催化棕榈酰辅酶A和蛋白半胱氨酸转化为S-棕榈酰蛋白和辅酶A。如ZDHHC1、ZDHHC5、ZDHHC6、ZDHHC7和ZDHHC18各自含有一种DHHC型锌指,通过它们向广泛范围的底物(包括H-ras、SNAP 25和GABAA R蛋白)传递棕榈酰转移酶活性。