FITC标记的造血干细胞特异性相关结合蛋白3抗体-抗体-抗体-生物在线
FITC标记的造血干细胞特异性相关结合蛋白3抗体

FITC标记的造血干细胞特异性相关结合蛋白3抗体

商家询价

产品名称: FITC标记的造血干细胞特异性相关结合蛋白3抗体

英文名称: Anti-HS1BP3/FITC

产品编号: HZ-11568R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-HS1BP3/FITC Conjugated antibody 

FITC标记的造血干细胞特异性相关结合蛋白3抗体

 

产品编号 bs-11568R-FITC
英文名称 Anti-HS1BP3/FITC
中文名称 FITC标记的造血干细胞特异性相关结合蛋白3抗体
别    名 ETM2; FLJ14249; H1BP3_HUMAN; HCLS1 binding protein 3; HCLS1-binding protein 3; HS1 binding protein 3; HS1 BP3; HS1-BP3; HS1-binding protein 3; Hs1bp3; HSP1BP-3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  干细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HS1BP3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.

Function:
May be a modulator of IL-2 signaling.

Subunit:
Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro 

Similarity:
Contains 1 PX (phox homology) domain.

Database links:
Entrez Gene: 64342 Human
Entrez Gene: 100338217 Rabbit
Omim: 609359 Human
SwissProt: Q53T59 Human
Unigene: 531785 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

HS1BP3是含有一个PX(PHOX同源)结构域,392个氨基酸的蛋白质,亮氨酸拉链,基于免疫受体酪氨酸的抑制基序基序和多个富含脯氨酸的区域。主要在脑中表达,HS1BP3由人类染色体2p24.1的基因编码。编码HS1BP3的基因在家族性原发性震颤中经常发生突变,这是一种以运动性震颤、手、声音或头部为特征的疾病,但与帕金森病无相关性。HS1BP3与HAX-1的SH3结构域相互作用,也可能参与儿茶酚胺和5-羟色胺代谢的调节。HS1BP3作为IL-2信号通路的调节因子,可能参与淋巴细胞的活化。