FITC标记的同源盒蛋白转录因子EN2抗体
产品名称: FITC标记的同源盒蛋白转录因子EN2抗体
英文名称: Anti-EN2/FITC
产品编号: HZ-11552R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EN2/FITC Conjugated antibody
FITC标记的同源盒蛋白转录因子EN2抗体
产品编号 | bs-11552R-FITC |
英文名称 | Anti-EN2/FITC |
中文名称 | FITC标记的同源盒蛋白转录因子EN2抗体 |
别 名 | AUTS 1; AUTS1; EN 2; Engrailed 2; Engrailed homeo box 2; Engrailed homeobox 2; Engrailed homolog 2; Engrailed2; Homeobox protein engrailed 2; Homeobox protein engrailed2; Hu En 2; HuEn2; MabEn; HME2_HUMAN; Homeobox protein engrailed-2; Homeobox protein en-2; Hu-En-2. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 神经生物学 信号转导 干细胞 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 34kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EN2/Engrailed 2 (281-333aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]. Function: EN1 and EN2 encode homeodomain containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. EN2 may play a role in susceptibility to autism spectrum disorders. Subcellular Location: Nuclear. DISEASE: Note=Genetic variations in EN2 may be associated with susceptibility to autism. Similarity: Belongs to the engrailed homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 2020 Human Entrez Gene: 13799 Mouse Entrez Gene: EN2 Rat Omim: 131310 Human SwissProt: Q05917 Chicken SwissProt: P19622 Human SwissProt: P09066 Mouse Unigene: 134989 Human Unigene: 4298 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
同源盒基因被认为在控制发育中起着一定的作用。在Drosophila,'EnGrNEN’(EN)基因在分割的发育过程中起着重要的作用,需要形成后部隔室。小鼠同系物En1和En2的不同突变产生了不同的发育缺陷,这些缺陷常常是致命的。人EngRIN同源物1和2编码同源结构域蛋白,并参与控制中枢神经系统发育过程中的模式形成。