FITC标记的神经内分泌转化酶2抗体
产品名称： FITC标记的神经内分泌转化酶2抗体
英文名称： Anti-PCSK2/Proprotein Convertase 2/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
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Rabbit Anti-PCSK2/Proprotein Convertase 2/FITC Conjugated antibody
FITC标记的神经内分泌转化酶2抗体
| 产品编号 | bs-11533R-FITC |
| 英文名称 | Anti-PCSK2/Proprotein Convertase 2/FITC |
| 中文名称 | FITC标记的神经内分泌转化酶2抗体 |
| 别 名 | KEX2 like endoprotease 2; KEX2-like endoprotease 2; NEC 2; NEC2; NEC2_HUMAN; Neuroendocrine convertase 2; PC2; PCSK2; Prohormone convertase 2; Proprotein convertase 2; Proprotein convertase subtilisin/kexin type 2; SPC2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 生长因子和 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Proprotein Convertase 2 (201-300aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]. Function: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Subcellular Location: Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules. Similarity: Belongs to the peptidase S8 family. Furin subfamily. Database links: Entrez Gene: 5126 Human Entrez Gene: 18549 Mouse Omim: 162151 Human SwissProt: P16519 Human SwissProt: P21661 Mouse Unigene: 315186 Human Unigene: 294493 Mouse Unigene: 447466 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码枯草杆菌蛋白酶样前体蛋白转化酶家族的成员。这些酶将潜在的前体蛋白加工成它们的生物活性产物。编码的蛋白质在生物合成中起着关键的作用，通过加工多种原，包括胰岛素原、原阿黑皮素和促前列腺素释放。该基因的单核苷酸多态性可能增加心肌梗死和2型糖尿病的易感性。该基因也可能在肿瘤的发生和发展中发挥作用。另一种编码多个异构体的剪接转录变体已被观察到。