FITC标记的锌指蛋白461抗体
产品名称： FITC标记的锌指蛋白461抗体
英文名称： Anti-GIOT1/FITC
产品编号： HZ-11406R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-GIOT1/FITC Conjugated antibody
FITC标记的锌指蛋白461抗体
| 产品编号 | bs-11406R-FITC |
| 英文名称 | Anti-GIOT1/FITC |
| 中文名称 | FITC标记的锌指蛋白461抗体 |
| 别 名 | GIOT-1; GIOT 1; Gonadotropin inducible ovary transcription repressor 1; Gonadotropin inducible transcription repressor 1; Gonadotropin-inducible ovary transcription repressor 1; Zinc finger protein 461; ZN461_HUMAN; ZNF461. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 生长因子和激素 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 66kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GIOT1/ZNF461 (191-240aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed, with highest levels in liver, kidney, pancreas, thymus, and small intestine. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 12 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 92283 Human Omim: 608640 Human SwissProt: Q8TAF7 Human Unigene: 590972 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GIOT-1是属于Kr upp-C2H2型锌指蛋白家族的563个氨基酸。在细胞核中，GIOT-1在组织中广泛表达，在肝脏、肾脏、小肠、胰腺和胸腺中的含量最高。GIOT-1含有12个C2H2型锌元素和一个KrAb结构域。由于KrAb结构域作为模板阻遏物在模板DNA的作用下，GIOT-1被认为参与转录调控。编码GIOT-1的基因定位于染色体19q1312，GIOT-1的两种异构体作为选择性剪接事件的结果而存在。