FITC标记的腺苷A1受体抗体
产品名称： FITC标记的腺苷A1受体抗体
英文名称： Anti-ADORA1/FITC
产品编号： HZ-6649R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749
- 传真 : 021-60345367
- 邮箱 : www.shzbio.net
Rabbit Anti-ADORA1/FITC Conjugated antibody
FITC标记的腺苷A1受体抗体
| 英文名称 | Anti-ADORA1/FITC |
| 中文名称 | FITC标记的腺苷A1受体抗体 |
| 别 名 | A1AR; A1R; AA1R; AA1R_HUMAN; Adenosine receptor A1; ADORA 1; ADORA1; RDC 7; RDC7; Ri. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 神经生物学 信号转导 细胞凋亡 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Adenosine A1 Receptor |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway. Function: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Subcellular Location: Cell membrane. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 134 Human Entrez Gene: 11539 Mouse Entrez Gene: 29290 Rat Omim: 102775 Human SwissProt: P28190 Cow SwissProt: P30542 Human SwissProt: Q60612 Mouse SwissProt: P25099 Rat Unigene: 77867 Human Unigene: 298908 Mouse Unigene: 32078 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
腺苷参与多种过程，包括尿素的合成、抗炎反应和蛋白质合成的抑制。腺苷受体，包括腺苷A1-R，腺苷A2A- R，腺苷A2B-R和腺苷A3-R，是膜蛋白的一个整体，是G蛋白偶联受体家族的成员。腺苷A1-R以部分钙依赖的方式介导尿素生成。腺苷已知通过腺苷A2A- R介导冠状动脉舒张，腺苷通过某些A2B受体作用于某些细胞中胶原合成和总蛋白合成被抑制。腺苷A3-R的激活抑制TNF的诱导？阻断内毒素CD14受体信号转导通路。