FITC标记的原癌基因wnt7a蛋白抗体-抗体-抗体-生物在线
FITC标记的原癌基因wnt7a蛋白抗体

FITC标记的原癌基因wnt7a蛋白抗体

商家询价

产品名称: FITC标记的原癌基因wnt7a蛋白抗体

英文名称: Anti-WNT7A/FITC

产品编号: HZ-6645R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

上海沪震实业有限公司
  • 联系人 : 鲍丽雯
  • 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 139****0749
  • 传真 : 021-60345367
  • 邮箱 : www.shzbio.net

 Rabbit Anti-WNT7A/FITC Conjugated antibody

FITC标记的原癌基因wnt7a蛋白抗体

 

英文名称 Anti-WNT7A/FITC
中文名称 FITC标记的原癌基因wnt7a蛋白抗体
别    名 Protein Wnt-7a; wnt 7a;Protein Wnt-7a precursor; proto-oncogene wnt7a protein; wingless-type MMTV integration site family, member 7A; WNT7A; WNT7A_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  信号转导  干细胞  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human WNT7A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts.

Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).

Subunit:
Interacts with PORCN.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.

DISEASE:
Defects in WNT7A are the cause of limb pelvis hypoplasia aplasia syndrome (LPHAS) [MIM:276820]. A syndrome of severe deficiency of the extremities due to hypo- or aplasia of one or more long bones of one or more limbs. Pelvic manifestations include hip dislocation, hypoplastic iliac bone and aplastic pubic bones. Thoracic deformity, unusual facies and genitourinary anomalies can be present.
Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS) [MIM:228930]; also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. 

Similarity:
Belongs to the Wnt family.

Database links:

Entrez Gene: 7476 Human

Entrez Gene: 533782 Cow

Entrez Gene: 607180 Dog

Entrez Gene: 100055450 Horse

Entrez Gene: 22421 Mouse

Entrez Gene: 100355697 Rabbit

Entrez Gene: 114850 Rat

Omim: 601570 Human

SwissProt: O00755 Human

SwissProt: P24383 Mouse

Unigene: 72290 Human

Unigene: 56964 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

用于七个跨膜受体的卷曲家族成员的配体。可能发育蛋白WNT-7A的信号允许Mulle管的性二形态发育。