FITC标记的免疫球蛋白A Fc段受体1抗体
产品名称: FITC标记的免疫球蛋白A Fc段受体1抗体
英文名称: Anti-FCAR/CD89/FITC
产品编号: HZ-6586R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
上海沪震实业有限公司
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Rabbit Anti-FCAR/CD89/FITC Conjugated antibody
FITC标记的免疫球蛋白A Fc段受体1抗体
英文名称 | Anti-FCAR/CD89/FITC |
中文名称 | FITC标记的免疫球蛋白A Fc段受体1抗体 |
别 名 | CD89; Fc alpha receptor; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 免疫学 细胞表面分子 细胞类型标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Rat, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 29kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FCAR |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. Tissue specificity; Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. Subunit: Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2. Subcellular Location: Isoform A.1: Cell membrane; Single-pass type I membrane protein. Isoform A.2: Cell membrane; Single-pass type I membrane protein. Isoform A.3: Cell membrane; Single-pass type I membrane protein. Isoform B: Secreted. Isoform B-delta-S2: Secreted. Tissue Specificity: Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene: 2204 Human Omim: 147045 Human SwissProt: P24071 Human Unigene: 659872 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
结合免疫球蛋白α的Fc区。介导多种功能,包括细胞因子的产生。
组织特异性;同种型A.1,亚型A.2和亚型A.3在血液和粘膜髓样细胞之间有差异表达。亚型A.1、异构体A.2和亚型A.3均在单核细胞中表达。亚型A.1和异构体A.2在肺泡巨噬细胞中表达,然而在肺泡巨噬细胞表面仅表达一种亚型。